Home > Thierry Latran Foundation > News > Thierry Latran Foundation Second Annual Scientific Meeting

The 2nd scientific meeting of the Foundation took place in the Hanover Medical school on May 12th and 13th 2011 before the 9th  ENCALS ( European Network for the Cure of ALS) meeting hosted by Pr Reinhard Dengler and Pr Susanne Petri.  A joint session took place on Friday with an invited speaker : Dr Philip A. Goliber, VP, Strategy and Portfolio at UCB . He  developed  the challenges of Pharma R&D and Drug Discovery in Orphan and Rare Diseases; a productive debate followed his lecture.



Program of the meeting

Thursday 12 May

Presentations by grantees of round 2009:


  • 14 h: Translational research into the role of the ephrin receptor EphA4 in the pathogenesis of ALS
Philip Van Damme
  • 14.30 h: Pathological neuro-immune interactions between the macrophages/microglial cells and the affected motor neurons in animal models of ALS
Severine Boillée
  • 15 h: Role of TDP43 in motor neurons through studying a unique Tdp43 mutant mouse
Elizabeth Fisher
  • 15.30 h: Novel gene therapy approach for motoneuron disease through broad delivery of death signalling inhibitors by astrocytes
Cédric Raoul
  • 16.30 h: Rescue of mitochondrial damage: new therapeutic strategies
Maria Teresa Carri
  • 17 h: Contribution of Metabolic Dysfunction to ALS Pathogenesis
Jean-Philippe Loeffler
  • 17.30 h: Role of the PGC-la system in the pathogenesis of ALS
Patrick Weydt
  • 18 h: TLF: status and perspectives
V de Broglie, TLF director


Programme du Vendredi 13 Mai


Maria Pennuto

Maria Pennuto

Presentations by grantees of round 2010: 


  • 8.30 h: Interplay between Androgenic/Anabolic Steroid and IGF-1 Signaling in Amyotrophic Lateral Sclerosis
Maria Pennuto


  • 9 h : Utilization of features of the early disease phenotypes in a zebrafish model of ALS for pharmacological screening to detect small molecule neuroprotective compounds.
Tennore M Ramesh         


  • 9.30h : Creation and characterization of in vitro and in vivo models to investigate the pathogenic mechanism of mutant FUS/TLS
Ludo Van Den Bosch      


  • 10h : Functional characterization of two novel susceptibility loci in sporadic ALS
Jan H. Veldink      


  • 11h : Human motor neurons derived from induced pluripotent stem (iPS) cells: a new approach for modeling and treating human sporadic ALS
Delphine Bohl

Year 1 of 2


  • 11.30h :  G-CSF in ALS: from mice to humans
Caterina Bendotti

Year 1 of 1


  • 12h : Modeling ALS with patient-derived pluripotent stem cells
Niels Geijsen

Year 1 of 1


  • 12.30h : Restoration of respiratory motor function through optogenetics neural implants
Ivo Lieberam