Publication of the project : EphA4 inhibition as a therapeutic strategy for ALS This project selected in 2013 was a continuation of the project selected in 2009 entitled : “Translational Research into the role of the ephrin receptor EphA4...
AB Science presented the results of the interim analysis of the study of masitinib in ALS. The planned enrolment was 381 patients, with a pre-planned futility analysis with 30% of patients enrolled treated for 48 weeks, and a pre-planned interim...
New insight into ALS disease origins leads to targeted novel therapies The Thierry Latran Foundation selected in 2013 the innovative project: Normalization of the blood-brain barrier deficiency in ALS with inhibitors of the Platelet-Derived Growth Factor CC (PDGF-CC) pathway. The...
To explore neuroinflammation to find a therapeutic pathway Cédric Raoul presents the main outcome of his project This project was selected during the first call for projects of the Thierry Latran Foundation to understand the molecular nature of the...
The annual meeting of the European Network for the Cure of ALS took place in May 2015 in Dublin. Following its objective to contribute to find a treatment, the Thierry Latran Foundation is an active supporter since 2011 as...
A revolutionary tool to find new therapeutic avenues The innovative project based on iPS cells proposed by Delphine Bohl was selected in 2010 Project. Her very interesting results have been recently published, she comments them for the Foundation Human induced...
The emerging understanding of the role of G-quadruplexes in neurodegenerative diseases raises new possibilities for therapeutic intervention The research project led by Pr Adrian Isaacs, Department of Neurodegenerative Disease, Institute of Neurology at UC, was selected in 2013. During...
The discovery of a prognostic biomarker in ALS Within the prestigious University of Oxford (ranked for 2014-2015 as number one University in Health Science by the Times Magazine), Dr. Martin Turner undertakes a cutting- edge research on biomarkers. ...
An important result: The ANGIOGENIN project opens the way to a pharmaceutical development of a new treatment. The only objective of the Thierry Latran Foundation is to accelerate research to find a treatment. The selected projects must of...
Optogenetically-Controlled Restoration of Muscle Function in ALS to control breathing in ALS patients without the need for mechanical ventilation This avant-guarde project is managed through a collaborative work between University College London, Dr Barney Bryson in the team of...