sept-16 |
Acta Neuropathologica |
Peripheral monocytes are functionally altered and invade the CNS in ALS patients |
J. Weishaupt, Allemagne |
2010 |
sept-16 |
Scientifc Reports |
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins |
E. Buratti, Italie |
2013 |
août-16 |
The EMBO journal |
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy |
K. De Vos, Angleterre |
2012 |
août-16 |
Acta Neuropathologica |
Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways |
J. Veldink, Hollande |
2010 |
avril-16 |
Brain |
Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosis |
L.Dupuis, France |
2012 |
avril-16 |
FEBS |
The TDP-43 N-terminal domain structure at high resolution |
E. Buratti, Italie |
2013 |
avril-16 |
PLOS Biology |
Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation |
E. Buratti, Italie |
2013 |
mars-16 |
Acta Neuropathologica |
Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis |
L.Dupuis, France |
2012 |
mars-16 |
Acta Neuropathologica |
Presymptomatic activation of the PDGFCC pathway accelerates onset of ALS neurodegeneration |
U. Eriksson, Suède |
2012 |
fév-16 |
Human Molecular Genetics |
TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor |
E. Buratti, Italie |
2013 |
janv-16 |
Journal of Neurology Neurosurgery & Psychiatry |
Neurofilaments in the diagnosis of motoneuron diseases: a prospective study on 455 patients |
M. Otto, Allemagne |
2011 |
janv-16 |
Annals of Neurology |
Neurofilament levels as biomarkers in asymptomatic and symptomatic familial amyotrophic lateral sclerosis |
M. Otto, Allemagne |
2011 |
oct-15 |
Nucleic acids research |
TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways |
E. Buratti, Italie |
2013 |
sept-15 |
frontiers in Cellular Neuroscience |
Developing electrical properties of postnatal mouse |
D. Zytnicki, France |
2011 |
août-15 |
Journal of Neurophysiology |
Potassium currents dynamically set the recruitment and firing properties of F- type motoneurons in neonatal mice |
D. Zytnicki, France |
2011 |
juin-15 |
ALS and Frontotemporal Degeneration |
The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis |
M. Turner, Angleterre |
2012 |
juin-15 |
Neurobiology of disease |
Modeling amyotrophic lateral sclerosis in pure human iPSc-derived motor neurons isolated by a novel FACS double selection technique |
D. Bohl, France |
2010 |
juin-15 |
The journal of Physical Chemistry Letters |
Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43 |
E. Buratti, Italie |
2013 |
juin-15 |
Neurology |
Neurofilament light chain, A prognostic biomarker in amyotrophic lateral sclerosis |
M. Turner, Angleterre |
2012 |
avr-15 |
Genomics |
Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci |
0. Hardiman, Irlande |
2013 |
avr-15 |
Annals of Clinical and Translational Neurology |
CSF neurofilament light chain reflects corticospinal tract |
M. Turner, Angleterre |
2012 |
avr-15 |
Neuroscience |
Motor neurons with differential vulnerability to degeneration show distinct protein signatures in health and ALS |
S. Corti, Italie |
2012 |
fev-15 |
Neuropharmacology |
First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models |
J. Kelly, Irlande |
2013 |
fev-15 |
Neurobiolgy of Aging |
A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis |
0. Hardiman, Irlande |
2013 |
janv-15 |
Prion |
The Structural Integrity of TDP-43 N-terminus is Required for Efficient Aggregate Entrapment and Consequent Loss of Protein Function |
E. Buratti, Italie |
2013 |
janv-15 |
Brain |
System xC− is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice |
S. Boillée, France |
2009 |
janv-15 |
Annals of Clinical and Translational Neurology |
SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice |
C. Raoul, France / P.Aebischer, Suisse |
2009 |
janv-15 |
Human Molecular Genetics |
TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain |
E. Buratti, Italie |
2013 |
janv-15 |
Cerebral Cortex |
Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis |
D. Zytnicki, France |
2011 |
oct-14 |
eLife |
Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis |
D. Zytnicki, France |
2011 |
sept-14 |
ALS Frontotemporal Degeneration |
Multicentre quality control evaluation of different biomarker candidates for amyotrophic lateral sclerosis |
M. Otto, Allemagne |
2011 |
sept-14 |
ALS Frontotemporal Degeneration |
Limited Role of Free TDP-43 as a Diagnostic Tool in Neurodegenerative Diseases |
M. Otto, Allemagne |
2011 |
août-14 |
Neurobiology of Aging |
Androgens affect muscle, motor neuron and survival in a mouse model of SOD1-related ALS |
M. Pennuto, Italie |
2010 |
juil-14 |
Annals of Neurology |
C9orf72 and UNC13A…: A genome-wide meta-analysis |
J. Veldink, Hollande |
2010 |
juin-14 |
Neurobiology of Aging |
Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy |
E. Fisher, Angleterre |
2009 |
mai-14 |
EMBO reports |
Somatic and axonal LIGHT signaling elicit degenerative and regenerative responses in motoneurons, respectively |
C. Raoul, France / P.Aebischer, Suisse |
2009 |
avr-14 |
Journal of Physiology |
Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis |
, D. Zytnicki, France |
2011 |
avr-14 |
Science |
OPTICAL CONTROL OF MUSCLE FUNCTION BY TRANSPLANTATION OF STEM CELL–DERIVED MOTOR NEURONS IN MICE |
I. Lieberam, Angleterre |
2010 |
mars-14 |
Archives of Biochemistry and Biophysics |
Structural characterization of the minimal segment of TDP-43 competent for aggregation |
E. Buratti, Italie |
2013 |
févr-14 |
Human Gene Therapy |
Intracerebroventricular Injection of Adeno-Associated Virus 6 and 9 Vectors for Cell Type–Specific Transgene Expression in the Spinal Cord |
C. Raoul, France / P.Aebischer, Suisse |
2009 |
févr-14 |
Neurobiology of Disease |
Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization |
A. Clément / C. Behl, Allemagne |
2009 |
févr-14 |
Frontiers in Cellular NeuroScience |
A plural role for lipids in motoneurone disease |
J. P. Loeffler / P. F. Pradat, France |
2009 |
janv-14 |
Neuroreport |
Cerebrospinal fluid-targeted delivery of neutralizing anti-IFNgamma antibody delays motor decline in an ALS mouse model |
C. Raoul, France / P. Aebischer, Suisse |
20O9 |
janv-14 |
PLoS ONE |
A Nonsense Mutation in Mouse Tardbp Affects TDP43 Alternative Splicing Activity and Causes Limb-Clasping and Body Tone Defects |
E. Fisher, Angleterre |
2009 |
nov.-13 |
Frontiers in Cellular Neuroscience |
Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis |
C. Raoul, France / P. Aebischer, Suisse |
20O9 |
oct.-13 |
Human Molecular Genetics |
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes. |
F. Hirth, Angleterre |
2011 |
sept.-13 |
Frontiers in Cellular Neuroscience |
Fatting the brain: a brief of recent research |
J. P. Loeffler / P. F. Pradat, France |
2009 |
juil-13 |
Journal of Proteomics |
Angiogenin induces modifications in the astrocyte secretome: Relevance to amyotrophic lateral sclerosis |
J. H. Prehn, Irlande |
2011 |
juin-13 |
PLoS ONE |
Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury |
J. P. Loeffler
/ P. F. Pradat, France |
2009 |
mai-13 |
Human Molecular Genetics |
PGC-1α is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis |
P. Weydt, Allemagne |
2009 |
mai-13 |
Brain |
Is SOD1 loss of function involved in amyotrophic lateral sclerosis? |
E. Fisher, Angleterre |
2009 |
févr-13 |
Brain |
Degeneration of serotonergic neurons in amyotrophic lateral sclerosis: a link to spasticity |
L. Dupuis, France |
2012 |
févr-13 |
Human Molecular Genetics |
Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish |
T. Ramesh, Angleterre |
2010 |
févr-13 |
Stem cells translational medicine |
Neural Progenitors Derived From Human Induced Pluripotent Stem Cells Survive and Differentiate Upon Transplantation Into a Rat Model of Amyotrophic Lateral Sclerosis |
D. Bohl, France |
2010 |
janv-13 |
Human Molecular Genetics |
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes |
F. Hirth, Angleterre |
2011 |
janv-13 |
Cell reports |
TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila |
F. Hirth, Angleterre |
2011 |
août-12 |
Nature Medicine |
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans |
P. Van
Damme, Belgique |
2009 |
mai-12 |
European Journal of Neurology |
Elevated levels of IFNγ and LIGHT in the spinal cord of patients with sporadic amyotrophic lateral sclerosise |
C. Raoul, France / P. Aebischer, Suisse |
2009 |
avr-12 |
PLoS ONE |
Mapping of Gene Expression Reveals CYP27A1 as a Susceptibility Gene for Sporadic ALS |
J. Veldink, Hollande |
2010 |
avr-12 |
Neurobiology of Aging |
VCP mutations in familial and sporadic amyotrophic lateral sclerosis |
J. Veldink, Hollande |
2010 |
avr-12 |
The Journal of Neuroscience |
Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia |
J.H. Prehn, Irlande |
2011 |
mars-12 |
Neurobiology of Aging |
UNC13A is a modifier of survival in amyotrophic lateral sclerosis |
J. Veldink, Hollande |
2010 |
févr-12 |
Pharmacological Research |
The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis |
M. Pennuto, Italie |
2010 |
janv-12 |
PLOS Genetics |
Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression |
J.Veldink, Hollande |
2010 |
nov-11 |
Human Molecular Genetics |
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation |
M.T. Carri, Italie |
2009 |
mars-11 |
Disease Models & Mechanisms |
A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis |
E. Fisher, Angleterre |
2009 |
nov-10 |
Cell Death and Differentiation |
IFNγ triggers a LIGHT-dependent selective death of motoneurons |
C. Raoul, France / P. Aebischer, Suisse |
2009 |