Home > Granted research > 58 publications on granted projects
Date Revue Principal investigator Year
sept-15 frontiers in Cellular Neuroscience Developing electrical properties of postnatal mouse D. Zytnicki, France 2011
aug-15 Journal of Neurophysiology Potassium currents dynamically set the recruitment and firing properties of F- type motoneurons in neonatal mice D. Zytnicki, France 2011
aug-15 Jama Neurology Heritability of Amyotrophic Lateral Sclerosis: Insights From Disparate Numbers. 0. Hardiman, Ireland 2013
june-15 FEBSletter G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome A. Isaacs, England 2013
june-15 ALS and Frontotemporal Degeneration The longitudinal cerebrospinal fl uid metabolomic profile of amyotrophic lateral sclerosis M. Turner, England 2012
june-15 Neurobiology of disease Modeling amyotrophic lateral sclerosis in pure human iPSc-derived motor neurons isolated by a novel FACS double selection technique D. Bohl, France 2010
june-15 Neurology Neurofilament light chain, A prognostic biomarker in amyotrophic lateral sclerosis M. Turner, England 2012
apr-15 Genomics Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci 0. Hardiman, Ireland 2013
apr-15 Annals of Clinical and Translational Neurology CSF neurofilament light chain reflects corticospinal tract M. Turner, England 2012
feb-15 Neuroscience Motor neurons with differential vulnerability to degeneration show distinct protein signatures in health and ALS S. Corti, Italy 2012
feb-15 Neurobiolgy of Aging A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis 0. Hardiman, Ireland 2013
jan-15 Brain System xC− is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice S. Boillée, France 2009
jan-15 Annals of Clinical and Translational Neurology SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice C. Raoul, France /   P.Aebischer, Suisse 2009
jan-15 Cerebral Cortex Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis D. Zytnicki, France 2011
oct-14 eLife Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis D. Zytnicki, France 2011
sept-14 ALS Frontotemporal Degeneration Multicentre quality control evaluation of different biomarker candidates for amyotrophic lateral sclerosis M. Otto, Germany 2011
sept-14 ALS Frontotemporal Degeneration Limited Role of Free TDP-43 as a Diagnostic Tool in Neurodegenerative Diseases M. Otto, Germany 2011
aug-14 Neurobiology of Aging Androgens affect muscle, motor neuron and survival in a mouse model of SOD1-related ALS M. Pennuto, Italy 2010
july-14 Annals of Neurology C9orf72 and UNC13A…: A genome-wide meta-analysis J. Veldink, Holland 2010
june-14 Neurobiology of Aging Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy E. Fisher, England 2009
may-14 EMBO reports Somatic and axonal LIGHT signaling elicit degenerative and regenerative responses in motoneurons, respectively C. Raoul, France / P.Aebischer, Switzerland 2009
apr-14 Journal of Physiology Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis D. Zytnicki, France 2011
apr-14 Science OPTICAL CONTROL OF MUSCLE FUNCTION BY TRANSPLANTATION OF STEM CELL–DERIVED MOTOR NEURONS IN MICE I. Lieberam, England 2010
febr-14 Human Gene Therapy Intracerebroventricular Injection of Adeno-Associated Virus 6 and 9 Vectors for Cell Type–Specific Transgene Expression in the Spinal Cord C. Raoul, France / P.Aebischer, Switzerland 2009
febr-14 Neurobiology of Disease Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization A. Clément / C. Behl, Germany 2009
febr-14 Frontiers in Cellular NeuroScience A plural role for lipids in motoneurone disease J. P. Loeffler / P. F. Pradat, France 2009
jan-14 Neuroreport Cerebrospinal fluid-targeted delivery of neutralizing anti-IFNgamma antibody delays motor decline in an ALS mouse model C. Raoul, France / P. Aebischer, Switzerland 20O9
jan-14 PLoS ONE A Nonsense Mutation in Mouse Tardbp Affects TDP43 Alternative Splicing Activity and Causes Limb-Clasping and Body Tone Defects E. Fisher, England 2009
nov.-13 Frontiers in Cellular Neuroscience Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis C. Raoul, France / P. Aebischer, Switzerland 20O9
oct.-13 Human Molecular Genetics Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes. F. Hirth, England 2011
sept.-13 Frontiers in Cellular Neuroscience Fatting the brain: a brief of recent research J. P. Loeffler / P. F. Pradat, France 2009
july-13 Journal of Proteomics Angiogenin induces modifications in the astrocyte secretome: Relevance to amyotrophic lateral sclerosis J. H. Prehn, Ireland 2011
june-13 Journal of Neurodegenerative Diseases Angiogenin induces modifications in the astrocyte secretome: Relevance to amyotrophic lateral sclerosis C. Raoul, France / P. Aebischer, Switzerland 2009
june-13 PLoS ONE Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury J. P. Loeffler
/ P. F. Pradat, France		 2009
may-13 Human Molecular Genetics PGC-1α is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis P. Weydt, Germany 2009
may-13 Brain Is SOD1 loss of function involved in amyotrophic lateral sclerosis? E. Fisher, England 2009
febr-13 Human Molecular Genetics Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish T. Ramesh, England 2010
febr-13 Stem cells translational medicine Neural Progenitors Derived From Human Induced Pluripotent Stem Cells Survive and Differentiate Upon Transplantation Into a Rat Model of Amyotrophic Lateral Sclerosis D. Bohl, France 2010
jan-13 Human Molecular Genetics Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes F. Hirth, England 2011
jan-13 Cell reports TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila F. Hirth, England 2011
nov.-12 frontiers in Neuroscience Molecular Mechanisms in Amyotrophic Lateral Sclerosis: The Role of Angiogenin, a Secreted RNase J. Prehn, Ireland 2011
nov.-12 Antioxydants Redox Signaling Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention M. T. Carri, Italy 2009
aug-12 Nature Medicine EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans P. Van
Damme, Belgium		 2009
june-12 Traffic. HDAC6 at the Intersection of Neuroprotection and Neurodegeneration L. Van Den Bosch, Belgium 2010
may-12 Progress in Neurobiology Mitochondrial dysfunction in ALS M.T. Carri, Italy 2009
may-12 European Journal of Neurology Elevated levels of IFNγ and LIGHT in the spinal cord of patients with sporadic amyotrophic lateral sclerosise C. Raoul, France / P. Aebischer, Switzerland 2009
apr-12 PLoS ONE Mapping of Gene Expression Reveals CYP27A1 as a Susceptibility Gene for Sporadic ALS J. Veldink, Holland 2010
apr-12 Neurobiology of Aging VCP mutations in familial and sporadic amyotrophic lateral sclerosis J. Veldink, Holland 2010
apr-12 The Journal of Neuroscience Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia J.H. Prehn, Ireland 2011
march-12 Neurobiology of Aging UNC13A is a modifier of survival in amyotrophic lateral sclerosis J. Veldink, Holland 2010
febr-12 Pharmacological Research The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis M. Pennuto, Italy 2010
jan-12 PLOS Genetics Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression J.Veldink, Holland 2010
dec-11 Journal of Bioenergetics and Biomembranes SOD1 and mitochondria in ALS: a dangerous liaison. M.T. Carri, Italy 2009
nov-11 Human Molecular Genetics Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation M.T. Carri, Italy 2009
june-11 Mammalian Genome SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments E. Fisher, England 2009
march-11 Disease Models &amp Mechanisms A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis E. Fisher, England 2009
jan-11 Journal of Biomedicine and Biotechnology Genetic rodent models of amyotrophic lateral sclerosis L. Van Den Bosch, Belgium 2010
nov-10 Cell Death and Differentiation IFNγ triggers a LIGHT-dependent selective death of motoneurons C. Raoul, France / P. Aebischer, Switzerland 2009
Granted research
VdB