Thierry Latran Foundation | Projects 2010 financed by the Fondation Thierry Latran |
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The second call for projects was again granted with an aggregate amount up to 1 million € . The topic were : Biological markers, pathological pathways and mechanisms, therapeutic strategies, innovative molecules in the fields ALS and protection of motor neurons with an additional specific topic on Stem cells therapeutic approaches in ALS The Foundation received 50 abstracts from all over Europe Each Scientific Advisory Board (SAB) member evaluated each abstract independently. Based on the consolidation, SAB met to propose a selection to the Bureau of the Foundation. 14 projects were selected for a full application.
The full application was assessed by two independent referees, their evaluation was presented by one SAB members to the other during a specific meeting. Projects have been ranked in A, B or C following the procedure. SAB president, Professor Wim Robberecht, presented the SAB proposal to the Executive Committee.
At the end 9 projects are selected
Maria Pennuto, Italy - Grant: € 125 0008 projects granted (1 project obtained a grant in between) Overall amount granted 911 000 € over 2 years Grantees were informed in July 2010 Grants started in September depending on the effective start of the project. Projects selected and granted 1. Interplay between androgenic/anabolic steroid and igf-1 signaling in amyotrophic lateral sclerosis Download PDF 2. Utilization of features of the early disease phenotypes in a zebrafish model of als for pharmacological screening to detect small molecule neuroprotective compounds. Tennore M.Ramesh, UK - Grant: € 30 000 Download PDF 3. Creation and characterization of in vitro and in vivo models to investigate the pathogenic mechanism of mutant fus/tls-induced ALS Ludo Van Den Bosch, Belgium - Grant: € 150 000 Download PDF 4. Human motor neurons derived from induced pluripotent stem (ips) cells: a new approach for modeling and treating human sporadic ALS. Delphine Bohl, France - Grant: € 160 000 Download PDF 5. G-CSF in Als: from mice to humans Caterina Bendotti, Italy - Grant: € 70 000 Download PDF 6. Modeling ALS with patient-derived pluripotent stem cells Niels Geijsen, The Netherlands - Grant: € 60 000 Download PDF 7. Restoration of respiratory motor function through optogenetic neural implants Ivo Lieberam, United Kingdom - Grant: € 80 000 Download PDF 8. Functional characterization of two novel susceptibility loci in sporadic ALS Jan H. Veldink, The Netherlands - Grant: € 200 000 Download PDF |
