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Home Thierry Latran Foundation News Thierry Latran Foundation Second Annual Scientific Meeting

All financed teams

Key Facts

• 100 % of the donations allocated to ALS research

• 5 calls for projetcs

• 29 teams funded

• 4 millions Euros for the first four calls for projects

Thierry Latran Foundation Second Annual Scientific Meeting

The 2nd scientific meeting of the Foundation took place in the Hanover Medical school on May 12th and 13th 2011 before the 9th  ENCALS (European Network for the Cure of ALS) meeting hosted by Pr Reinhard Dengler and Pr Susanne Petri.  A joint session took place on Friday with an invited speaker: Dr Philip A. Goliber, VP, Strategy and Portfolio at UCB. He  developed  the challenges of Pharma R&D and Drug Discovery in Orphan and Rare Diseases; a productive debate followed his lecture. groupe  
          Grantees 2009 & 2010 with the members of the Scientific Advisory Board 


Program of the meeting
Thursday 12 May

Presentations by grantees of round 2009:

14 h: Translational research into the role of the ephrin receptor EphA4 in the pathogenesis of ALS
Philip Van Damme

14.30 h: Pathological neuro-immune interactions between the macrophages/microglial cells and the affected motor neurons in animal models of ALS
Severine Boillée

15 h: Role of TDP43 in motor neurons through studying a unique Tdp43 mutant mouse
Elizabeth Fisher
 
15.30 h: Novel gene therapy approach for motoneuron disease through broad delivery of death signalling inhibitors by astrocytes
Cédric Raoul

16 h – 16.30 h : coffee break

16.30 h: Rescue of mitochondrial damage: new therapeutic strategies
Maria Teresa Carri
 
17 h: Contribution of Metabolic Dysfunction to ALS Pathogenesis
Jean-Philippe Loeffler
 
17.30 h: Role of the PGC-la system in the pathogenesis of ALS
Patrick Weydt
 
18 h: TLF: status and perspectives
Valérie de Broglie, TLF director

Friday 13 May 

Presentations by grantees of round 2010:

8.30 h: Interplay between Androgenic/Anabolic Steroid and IGF-1 Signaling in Amyotrophic Lateral Sclerosis
Maria Pennuto 
mariapennuto
 
9 h: Utilization of features of the early disease phenotypes in a zebrafish model of ALS for pharmacological screening to detect small molecule neuroprotective compounds.
Tennore M Ramesh
 
9.30 h Creation and characterization of in vitro and in vivo models to investigate the pathogenic mechanism of mutant FUS/TLS
Ludo Van Den Bosch
 
10 h Functional characterization of two novel susceptibility loci in sporadic ALS 
Jan H. Veldink
janhveldink
 

10h30 coffee break 

11h: Human motor neurons derived from induced pluripotent stem (iPS) cells: a new approach for modeling and treating human sporadic ALS
Delphine Bohl 
dbohl

11h 30: G-CSF in ALS: from mice to humans
Ilaria Caron for Caterina Bendotti
ilariacaron

12 h: Modeling ALS with patient-derived pluripotent stem cells 
Niels Geijsen
nielsgeijsen 

12h30: Restoration of respiratory motor function through optogenetics neural implants
Ivo Lieberam
ivolieberam