Home > Granted research > 2017 – 9th Call for Projects: Selected Projects

The Thierry Latran Foundation 9th  Call for projects  opened in November 2016

to finance research with potential therapeutic benefit in sporadic ALS on the following themes:

Biological markers, pathological pathways and mechanisms, therapeutic strategies, innovative molecules in the fields of ALS and protection of motor neurons.

Submission of clinical or patient centric/oriented research projects were particularly encouraged

We received 86  abstracts coming from 13 different countries

 Since inception, 709 projects were submitted to the Foundation.

 Selection process:

Each Member of the Scientific Advisory Board (SAB), assessed independently the 82 abstracts taking into account their scientific quality and their relevance to the objectives of the Foundation. During the process, the members of the Scientific Committee with a conflict of interest did participate neither to assessment nor to discussion.

These assessments have been consolidated and anonymized. A meeting of the Scientific Committee was held in February 20167for selection, validated by the Foundation. 13 projects were selected for full application.

Each of the 13 application was analyzed by 2 different ‘referees’, specialized on the theme of the project and having no connection with the applicants.  The members of the Scientific Committee met in May to assess the projects on the basis of the opinion of the “referees” and to classify them into 3 groups A (strong recommendation for funding) B (projects recommended to be financed according to the available budget) and C (projects not recommended for funding). The SAB’s recommendations were presented to the Executive Committee in June 2017.

At the end, six projects were selected, meeting the selection criteria i.e. scientific excellence and contribution to the development of a therapy.

Project 1 : GeneTherC9

Martine BARKATS, CNS gene transfer and biotherapy of motor neuron diseases, Center of Research in Myology, Paris, France

1. GeneTherC9

Project 2: IS- ALS

Stefania CORTI,Department of   Pathophysiology and Transplantation- Neural Stem Cells Lab, University of Milan, Italy


Project 3 : Aggregated-TDP43

Markus OTTO, Department of Neurology, Ulm University, Germany

3. Aggregated-TDP43

Project 4 : TDPBAC

 Kevin TALBOT, Nuffield Department of Clinical NeuroSciences, University of Oxford, Great Britain


Project 5 : ALS- OL

 Catherine VERFAILLIE, Stem Cell Insitute, KU Leuven, Belgium

Cartoon on the role of mutant oligodendrocytes


Project 6 : MultiMono

 Jochen WEISHAUPT, Neurology Department, Ulm University, Germany

6. MultiMono

The Thierry Latran Foundation is extremely grateful for the excellent work done by

Pr Wim Robberecht (Leuven University, Belgium) (President)

Pr Caterina Bendotti (Mario Negri Institute,  Milano, Italy)

Pr Leonard H van den Berg (Utrecht University, The Netherlands) 

Dr Séverine Boillée (ICM, Paris, France)

Dr Jan Egebjerg (Lundbeck, Denmark)

Pr Linda Greensmith (University College of London, UK)

Pr Eva Hedlund (Karolinska Institute, Stockholm, Sweden)

Pr Albert Ludolph (Ulm University, Germany)

Elke Bogaert , SAB secretary  (PHD in Neurosciences, Leuven) who drove the process.